In recent years, there has been a renewed interest in plants as pharmaceuticals with the discovery of new biologically-active molecules from crude extracts of plants. A large number of medicinal plants continue to provide valuable therapeutic agents for the treatment of a broad spectrum of diseases throughout the world. Cissus rotundifolia is a perennial, evergreen, climber, wild plant belonging to the family Vitaceae. It is a new source for bioactive phytoconstituents with various health benefits. This herbal plant represents remarkable antioxidant, antibacterial, analgesic, anti-inflammatory, and anti-ulcerative activities. In this issue, Gumaih et al. reported the potential of the methanolic leaves extracts of C. rotundifolia, as an anti-urolithic and antihypertensive agent in albino rats. C. rotundifolia can be a potential source of valuable therapeutic agents and further investigations should be undertaken in this case in the future.Keywords: Cissus rotundifolia, medicinal plant, therapeutic agents, leaves extract.Citation: Iqbal, M.N., Ashraf, A., 2020. Cissus rotundifolia: a Potential Source of Valuable Therapeutic Agents. Int. J. Nanotechnol. Allied Sci., 4(2): IJNAS-2020-044.