An examination of methanol extract of Capparis cartilaginea leaves showed isolation of 4 terpenoid compounds characterized as 3,9-Dihydroxygermacra-4,10,11-triene, 6-Methoxyeudesm-4-en-1-ol, Gallic acid, and 3,4-Dihydroxybenzoic acid. Structure elucidations were carried out by spectroscopy methods.Keywords: Capparis cartilaginea leaves, Sesquiterpenes compounds, NMR analysis.Citation: Al-Mahweety, J.A.N., 2020. Sesquiterpenes Compounds from the Leaves of Capparis cartilaginea. PSM Biol. Res., 5(2): 74-78.