There is a great interest in combining anticancer drugs with natural products aiming at maximizing their efficacy while minimizing systemic toxicity. Milk thistle (Silybum marianum) was used against chemotherapy-induced organ toxicity. Screening for natural substances with chemopreventive properties in order to reduce the negative effects of chemotherapeutic drugs is very urgent.Read more,,,,,,Citation: Iqbal, M.N., Ashraf, A., 2020. Milk thistle (Silybum marianum) as a Promising Chemoprotective Agent for Liver Therapy. PSM Biol. Res., 5(1): BR-2020-015.