A Review of Biological Activities of Genus Croton

Author's: Ibrahim Ali Al-Hakami1, Salwa Raweh1, Amina El-Shaibany1, Abdulrahman Humaid2,3*, Mahmoud Elaasser4
Authors' Affiliations
1Pharmacognosy Department, Pharmacy College, Sana`a University, Sanaa, Yemen.2Department of Biology, Faculty of Science, Sana`a University, Sanaa, Yemen.3Department of Pharmacy, Faculty of Medical Science, Modern Science University, Sana`a, Yemen.4The Regional Center for Mycology and Biotechnology, Al-Azhar University, 11787, Nasr City, Cairo, Egypt.
*CorrespondenceAbdulrahman HumaidEmail:humaidyemen@yahoo.com
Article Type: Mini-Review     Published: Mar. 08, 2022 Pages: 12-18
DOI:        Views 243       Downloads 0


Croton contains a wide range of constituents, including phorbol esters, alkaloids, di and triterpenoids such as clerodane, uphold derivatives, and flavonoids and their glycosides, all of which have medicinal value. In addition, several Croton species have a red sap, which contains proanthocyanins and/or alkaloids in some species. Some species are aromatic because they contain volatile oil. The current review summarizes the most important biological activities of Croton species for future research as potential medicines. It is important to note that the presence of secondary metabolite classes in Croton is a point worth considering because it could lead to the discovery of pharmacologically active substances.


Biological activities,

Pharmacology of Croton,


Potential medicines.

Authors’ Contribution

AE conceived and designed the study; IAA, ME, and SR wrote, revised the paper. AE and AH gave final approval for publication of the paper.

How to cite

Al-Hakami, I.A., Raweh, S., El-Shaibany, A., Humaid, A., Elaasser, M., 2022. A Review of Biological Activities of Genus Croton. PSM Microbiol., 7(1): 12-18.


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