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Nanoparticles are defined as particles between 1 and 1000 nm that have a range of unique properties. Nanoparticles have attracted much attention in recent years for their potential applications in biomedical research including drug and gen delivery (Guo et al., 2010), bioimaging (Tiwari et al., 2011), vaccine development (Niikura et al., 2013), biosensors, and therapies (Nicol et al., 2015).

Gold nanoparticles have been often studied due to their unique surface, chemical inertness, high electron density, and strong optical absorption. In recent decades, gold nanoparticles have been applied in genomics (Guo et al., 2010), clinical chemistry (Saha et al., 2012), vaccine development (Pokharkar et al., 2011), immunoassay (Hall et al., 2011), biosensors (Zayats et al., 2005), diagnosis, and microorganisms control (Pissuwan et al., 2010), cancer-cell imaging, and drug delivery (Pivodova et al., 2015).