Stem cell therapy is used for treatment of many diseases like diabetes, ischemia, Parkinson’s disease, cardiac and neurodegenerative diseases. Stem cells can be differentiated into many new types as they are actually undifferentiated cells. Cardiac disease is life threatening disorder. Any type of injury to heart muscles increase risk factors for myocardial infarction. Studies indicate that different stem cells are used for improvement of ventricular function by transplantation. New cardiac tissue cannot be formed but transplanted stem cells have paracrine effects that may be limited by teratoma formation. Brain has specific formation of substitution connection to the confined and compact action of neuronal stem cells respectively. This demonstrates nervous abnormality and series of neurodegenerative infections that shows a critical civil issue of our inhabitants. So, a competent analysis is motivated using stem cell therapy as a key. Then comparisons of different studies for treatment of different individuals who are suffering from neurodegenerative diseases are done. Different actions are taken that show aims for charge of NP afflicted individuals. This review sums up the current scenario of stem cell therapy in Cardiac and Neurodegenerative disorders.


Stem cells, neurodegenerative pathologies, stem cell therapy, cardiac disorders.


Irfan, M., Sajjad, U., Iqbal, M.N., 2019. Modern Stem Cell Therapy of Cardiac and Neurodegenerative Disorders: Pluses and Minuses. PSM Biol. Res., 4(1): BR-2018-065.